![]() ![]() Although these side-effects are still rare, they are slightly more likely to occur after Moderna than after Pfizer. The risk of side-effects also depends on the age of the person and on the vaccine. These inflammatory conditions are seen most often in boys and younger men between 12 and 30 years old. ![]() The incidence of myocarditis and pericarditis ranges between 1 and 10 in 100,000 people per year. People who have these symptoms should consult their doctor. The symptoms can vary significantly and usually improve on their own or can be treated effectively with medication. Symptoms include shortness of breath, chest pain and a forceful heartbeat that may sometimes be irregular. The reports indicate that the cases of myocarditis and pericarditis mostly started within the first fourteen days after vaccination, and were more likely to occur after the second vaccination than after the first. This has been established by the European Medicines Agency (EMA) after reviewing reports from countries within Europe and beyond. In very rare cases, inflammatory diseases of the heart may occur following vaccination with Pfizer or Moderna: myocarditis (inflammation of the heart muscle) or pericarditis (inflammation of the outer lining of the heart). The website of the Dutch Medicines Agency (CBG-MEB) also offers more information about AstraZeneca and Janssen (in Dutch). More information is available on the page about AstraZeneca side-effects. If these symptoms do occur, they are usually seen within three weeks after vaccination.
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